Current DNA sequencing platforms can analyze tens of thousands individual genomes per year, enabling large-scale population genomics. Detection of sequence variants is ideally performed in the context of the entire cohort, begging for thousands of samples to be analyzed in parallel. This is a computational and bandwidth challenge due to the huge amount of data that needs to be processed. In this white paper, the novel GENALICE MAP Population Calling module is presented, which is an extension of the GENALICE MAP NGS data analysis suite. It is a fully scalable module that adds individual samples to a larger cohort using an incremental approach.
In this white paper you will learn:
- How genotyping populations leads to enhanced genetic content?
- What are the current restrictions of population scale analysis?
- How GENALICE MAP performs population calling?
- How does GENALICE MAP compare to other NGS data analysis workflows?